Basement Membrane Extract (BME)-free Database

Basement Membrane Extract (BME)-free Database

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ECMatrix-511 Silk E8 Laminin Substrate

Merck, Sigma-Aldrich
https://www.sigmaaldrich.com/NL/en/product/mm/cc1611050ug, https://www.sigmaaldrich.com/NL/en/product/mm/cc161100ml
Natural

Human recombinant laminin-511 protein (0.5 mg mL−1; truncated). Produced by a silkworm expression system instead of expressed in CHO-S cells. This product is similar to iMatrix-511 silk from Matrixome.

Coating

2D
Embryonic stem cells (ESCs), Induced pluripotent stem cells (iPSCs)
Yes
Yes
Yes
Unspecified
No
Please note that recombinant laminins can be used to (bio)functionalise other products/hydrogels with to improve cellular functionality (e.g., cell adhesion, survival/proliferation, migration, differentiation and/or other cell type-specific responses).
Unspecified
Unspecified
Yes

Protocol – Coating

Contact us: 3RCU@uu.nl
3Rs Centre Utrecht  
Utrecht University
Bolognalaan 50 3584 CJ 
Utrecht, The Netherlands

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The development of the Basement Membrane Extract (BME)-free Database has been supported by Proefdiervrij

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