Cellendes
Natural, Synthetic
Dextran-based hydrogel
Dextran is covalently crosslinked by CD-Link via the Michael addition reaction. CD-Link is a metalloproteinase (MMP)-cleavable peptide conjugated to polyethylene glycol (PEG).
3D
Spheroids, Other
451Lu (RRID:CVCL_6357)
A-375 (RRID:CVCL_0132)
Hep-G2 (RRID:CVCL_0027)
Malme-3M (RRID:CVCL_1438)
NIH 3T3 (RRID:CVCL_0594)
WM1346 (RRID:CVCL_W886)
WM1366 (RRID:CVCL_6789)
A-375 (RRID:CVCL_0132)
Hep-G2 (RRID:CVCL_0027)
Malme-3M (RRID:CVCL_1438)
NIH 3T3 (RRID:CVCL_0594)
WM1346 (RRID:CVCL_W886)
WM1366 (RRID:CVCL_6789)
Yes
Yes
Yes
Specified
G’ = 20−10,000 Pa
Yes
Thiol-mediated conjugation. 3-D Life peptides or custom-made peptides with thiol groups can be covalently attached to the hydrogel.
Yes
Enzymatic digestion by 3-D Life Dextranase.
Yes
No
Yes
High-throughput screening, Organ-on-a-chip model