Cellendes
Synthetic
Hydrogel based on polyvinyl alcohol (PVA).
PVA is covalently crosslinked by CD-Link via the Michael addition reaction. CD-Link is a metalloproteinase (MMP)-cleavable peptide conjugated to polyethylene glycol (PEG).
3D
Spheroids, Other
Unspecified
Yes
Yes
Yes
Specified
G’ = 20−10,000 Pa
Yes
Thiol-mediated conjugation. 3-D Life peptides or custom-made peptides with thiol groups can be covalently attached to the hydrogel.
Yes
Enzymatic digestion by trypsin.
Yes
No
Yes
High-throughput screening, Organ-on-a-chip model