Biolaminin 521 MX (MX521) | Basement Membrane Extract (BME)-free Database

Commercial source

BioLamina

URL

https://biolamina.com/products/biolaminin-521-mx/

Product details

Origin

Natural

Type of material

Human recombinant laminin-521 protein (0.1 mg mL⁻¹; full-length; material for pre-clinical phase)

Type of gelation/Coating

Coating

Type of in vitro culture

Type of application

Embryonic stem cells (ESCs), Induced pluripotent stem cells (iPSCs)

Cell type

Primary cells

Eye

Photoreceptor cells

Retinal pigment epithelial (RPE) cells

Heart

Cardiac progenitor cells

Cardiomyocytes

Liver

Hepatocytes

Nervous system

Neurons

Pancreas

Beta cells

Skin

Keratinocytes

Stem cells

Adult stem cells

Mesenchymal stem/stromal cells (MSCs)

Embryonic stem cells (ESCs)

General

Induced pluripotent stem cells (iPSCs)

General

Pluripotent stem cells (PSCs)

General

Pluripotent stem cell (PSC)-derived cells

Embryonic stem cell (ESC)-derived cells

Endothelial progenitor cells (EPCs)

Hepatocytes

Retinal pigment epithelial (RPE) cells

Induced pluripotent stem cell (iPSC)-derived cells

Megakaryocytes

Pluripotent stem cell (PSC)-derived cells

Cardiomyocytes

Neural crest cells

Product specifications

Commercially available

Yes

Animal-free

Yes

Chemically defined

Yes

Mechanical properties

Unspecified

Possibility to conjugate biomolecules

Please note that recombinant laminins can be used to (bio)functionalise other products/hydrogels with to improve cellular functionality (e.g., cell adhesion, survival/proliferation, migration, differentiation and/or other cell type-specific responses).

Application specifications

Support maintenance pluripotency (PSCs)

Yes

Imaging

Autofluorescent

Transparent

Yes

Instructions

Product instructions

Instructions for use
Protocol – Culturing ESCs and iPSCs on Biolaminin 521

Downstream analysis

Protocol – Embryoid body formation from PSCs cultured on Biolaminin 521