ECMatrix-511 E8 Laminin Substrate | Basement Membrane Extract (BME)-free Database

Commercial source

Merck, Sigma-Aldrich

URL

https://www.sigmaaldrich.com/NL/en/product/mm/cc160350ug, https://www.sigmaaldrich.com/NL/en/product/mm/cc1601050ug, https://www.sigmaaldrich.com/NL/en/product/mm/cc160100ml

Product details

Origin

Natural

Type of material

Human recombinant laminin-511 protein (0.5 mg mL⁻¹; truncated). This product is similar to iMatrix-511 from Matrixome.

Type of gelation/Coating

Coating

Type of in vitro culture

Type of application

Embryonic stem cells (ESCs), Induced pluripotent stem cells (iPSCs)

Cell type

Stem cells

Embryonic stem cells (ESCs)

General

Induced pluripotent stem cells (iPSCs)

General

Pluripotent stem cells (PSCs)

General

Product specifications

Commercially available

Yes

Animal-free

Yes

Chemically defined

Yes

Mechanical properties

Unspecified

Possibility to conjugate biomolecules

Please note that recombinant laminins can be used to (bio)functionalise other products/hydrogels with to improve cellular functionality (e.g., cell adhesion, survival/proliferation, migration, differentiation and/or other cell type-specific responses).

Application specifications

Support maintenance pluripotency (PSCs)

Yes

Imaging

Autofluorescent

Unspecified

Transparent

Yes

Instructions

Product instructions

Protocol – Coating